RP-10
OSNA pretreatment system
- From tissue to lysate in 90 seconds
- Throughout lymph node tissue homogenisation
- Safely closed system for fresh tissue homogenisation
OSNA – One Step Nucleic Acid Amplification – is an automated rapid molecular diagnostic test for the detection of lymph node (LN) metastases. It analyses the entire LN tissue using a reverse transcriptase loop-mediated isothermal amplification reaction (RT-LAMP*) to quantify tumour-specific cytokeratin 19 (CK19) mRNA expression in LNs.
The pretreatment system RP-10 is an accessory to the OSNA automated molecular diagnostic test.
RP-10 is an instrument to homogenise lymph nodes prior to measurement by the Gene Amplification Detector RD-210. Homogenisation is performed using the reagent “LYNORHAG” in combination with the disposable “LYNOPREP BLADE SET”.
This instrument can homogenise up to 4 lymph node samples at the same time, taking about 1 minute 30 seconds from the start to the end of the homogenisation process.
* licensed under the agreement with Eiken Chemical CO., LTD
LYNOPREP BLADE SET (cat #AK186696) is an accessory for the OSNA automated molecular diagnostic test. Composed of containers and blades for the automated and effective homogenisation of lymph node tissues by the RP-10 pretreatment system.
LYNORHAG (cat #CL485270) is a buffer for the lysis of cells derived from mechanically homogenised human lymph node tissue. LYNORHAG is intended to be used for the preparation of samples from surgically removed lymph node(s) for use with the OSNA automated molecular diagnostic test. LYNORHAG is intended for use exclusively in association with the Gene Amplification Detector RD-210, pretreatment system RP-10 and LYNOAMP CK19 E.
| Article number | CL485270 |
| Capacity | 110 mL, 27 OSNA samples |
| Components | Glycine 200 mmol/L Dimethylsulfoxide 20% Detergent 5% |
| Dimensions box | W50 mm x D50 mm x H104 mm |
| Weight box | total 145 g; bottle only 115 g |
| Storage conditions | 2 to 8 °C |
| Shelf life | 12 months after production |
| In-use expiry | 2 months after opening |
| Article number | BL085582 |
| Throughput | Max. 4 tests per run (90 s) |
| Dimension | W391 mm x D267 mm x H500 mm |
| Weight | ~23 kg |
| Reagents | LYNORHAG |
| Disposables | LYNOPREP BLADE SET |
| Parameter | rpm |
Sysmex Europe SE
Bornbarch 1
22848 Norderstedt
Germany
+49 (40) 527 26 0
+49 (40) 527 26 100
OSNA complete video training.
These trainings are intended for pathologists and everyone who operates the instrument.
Product documents
Regulatory documents
Regulatory documents, such as Instructions for Use, can be accessed with a valid My Sysmex login:
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