XN Blood Bank mode
Perform the quality control of your blood products on one haematology analyser
Blood component safety is key in transfusion medicine and blood product manufacturing. Therefore, high standards during the whole process from donor qualification to quality monitoring of the products are required.
Especially residual cell enumeration is important for process quality control. Until now, haematology analysers could not reach the lower limit of quantification required for this. But now, the new Blood Bank mode offers the potential to run such analyses with confidence.
Your benefits in daily routine
- Say good-bye to current methods which are often time-consuming, costly and dependent on the individual skills of the staff.
- No manual preparation, so simple to operate for everyone in the laboratory.
- Consistent, standardised and automated assessment of the quality of your blood products to ensure patient safety
- Save precious time by analysing various parameters on one instrument.
- Accurately and reproducibly identify those blood components in which leucodepletion has failed.
- The Blood Bank mode is CE IVD compliant.
Donor safety, blood component safety, patient care
Blood components and measuring profiles
The Blood Bank mode offers the analysis of blood components with four different selectable profiles – two profiles for red blood cell concentrates and two profiles for platelet concentrates. . Plasma packs can be measured in the profile for platelet concentrates and residual cells.
RBC pack + residual cells
- rWBC Residual white blood cells
- RBC Red blood cell count
- HGB Haemoglobin
- HCT Haematocrit
RBC pack
- RBC, HGB, HCT
Aspirated sample volume
- 150 µL
PLT pack + residual cells
- rWBC Residual white blood cells
- rRBC* Residual red blood cells
- PLT Platelet count
PLT pack
- PLT
Aspirated sample volume
- 205 µL
PLT pack + residual cells (used for plasma pack analysis)
- rWBC Residual white blood cells
- rRBC* Residual red blood cells
- PLT Platelet count
Aspirated sample volume
- 205 µL
*parameter for research
Technical requirements
The XN-1000 and XN-2000 haematology analysers can now be equipped with the Blood Bank mode offering the potential to automate, simplify and rationalise the transfusion medicine and blood manufacturing workflow. The XN analyser has to be equipped with the RET and PLT-F applications and a Blood Bank mode licence.
Throughput
The hourly throughput of one standalone XN-1000 analyser in Blood Bank mode varies depending on the profiles used.
| Blood pack | Residual cell counts | Throughput | Time per single measurements |
| RBC pack | No Yes | 79 samples/h 33 samples/h | Less than 1 min Less than 2 min |
| PLT pack | No Yes | 62 samples/h 19 samples/h | Approx. 1 min Approx. 3 min |
Quality Control
The Blood Bank mode comes with a specifically designed QC mode, dedicated to the special requirements of blood products. This mode allows the application of three different control materials for the quality assessment of the Blood Bank mode.
XN Check
- Parameters RBC; HGB; HCT; PLT
XN Check BF
- Parameters WBC; For residual white blood cell monitoring!
Platelet Check
- Parameters PLT; For high level PLT monitoring!
Your benefits as our customer
International guidelines require blood component safety and therefore residual cell enumeration is crucial.
Current methods for the enumeration of rWBC and rRBC are either manual methods such as visual inspection and chamber counting or semi-automated methods such as flow cytometry or fluorescent image analysis. All of these methods require manual sample preparation and skilled staff, and are therefore not standardised.
Workflow improvements with the Blood Bank mode:
- Methods are standardised
- Easy to operate for everyone
- Consolidation of multiple haematological parameter on one platform
- No additional tube sampling
- Fully automated measurement in sampler mode
Videos QC material preparation
For XN Check, XN-L Check, XN Check BF, XN Cal, XN Cal PF, Eightcheck-3WP, SCS-1000
For Platelet Check
