Scientific documents library

The lab card illustrates the value of the DIFF application and points to the advanced clinical parameter IG (immature granulocytes). The front side addresses the lab and clinical benefits, the flip side contains technical information.

The early differentiation of the underlying cause of canine anaemia is one of the biggest diagnostic challenges for veterinary clinicians. The reticulocyte count, together with the study of the different circulating degrees of maturity may allow a much more thorough and detailed assessment of each patient in the veterinary lab. In this preliminary study, reference ranges have been established for reticulocyte maturity fractions. Following the assessment of more than 150 anaemic patients, the Ecija-Mendoza diagram was created, a diagnostic tool that allows the differentiation between conditions caused by haemolysis, acute haemorrhage and anaemia due to dyserythropoiesis to allow the clinician to quickly form a suspected diagnosis.

PLT counts alone do not reveal the underlying aetiology of thrombocytopenia. The causes of thrombocytopenia can be due to decreased platelet production in bone marrow or an increased destruction/consumption of platelets in peripheral blood. The IPF is a diagnostic parameter that can support treating physicians when determining the cause of thrombocytopenia based on the aetiology of various congenital and acquired thrombocytopenic states, as described in this white paper.