Scientific Image Gallery
Welcome to our Scientific Image Gallery. Here you can find real-life examples of cell images, mostly (but not only) from peripheral blood films, that illustrate typical morphologic characteristics pointing to specific conditions or disorders. This constitutes their diagnostic value.
Click on an image to enlarge it and display a short description.
This peripheral blood film (May-Grünwald-Giemsa stain) is from a patient with PMF (also called CIMF) in the prefibrotic stage. You can see scattered teardrop cells (->). Furthermore, a few granulocytic precursors and very few erythroblasts were detected (not shown). The automated cell count showed slight leukocytosis, thrombocytosis and anaemia.
<p>This peripheral blood film (May-Grünwald-Giemsa stain) is from a patient with PMF (also called CIMF) in the prefibrotic stage. You can see scattered teardrop cells (->). Furthermore, a few granulocytic precursors and very few erythroblasts were detected (not shown). The automated cell count showed slight leukocytosis, thrombocytosis and anaemia.</p>
Cell description:
Size: 10-18 µm, smaller than lymphoblast
Nucleus: round with coarser structure than a lymphoblast, one distinct nucleolus
Cytoplasm: blue without granules
<p>Cell description: </p> <p>Size: 10-18 µm, smaller than lymphoblast </p> <p>Nucleus: round with coarser structure than a lymphoblast, one distinct nucleolus </p> <p> Cytoplasm: blue without granules </p>
EDTA blood of a female patient with a transitional form of chronic lymphocytic leukaemia/prolymphocytic leukaemia. The three large cells are prolymphocytes, the smaller ones are lymphocytes.
<p>EDTA blood of a female patient with a transitional form of chronic lymphocytic leukaemia/prolymphocytic leukaemia. The three large cells are prolymphocytes, the smaller ones are lymphocytes.</p>
Cell description:
Size: bigger than monoblast
Nucleus: oval, kidney-shaped or lobulated, diffuse chromatin pattern, sometimes with nucleoli
Cytoplasm: pale basophil with fine azurophil granula.
Cell division is still possible.
<p>Cell description: </p> <p>Size: bigger than monoblast </p> <p>Nucleus: oval, kidney-shaped or lobulated, diffuse chromatin pattern, sometimes with nucleoli </p> <p>Cytoplasm: pale basophil with fine azurophil granula. </p> <p>Cell division is still possible.</p>
Cell description:
Size: 15-25 µm
Nucleus: oval with identifiable nucleoli and diffuse chromatin structure Cytoplasm: basophilic with visible golgi-zone and eye-catching azurophil granula (primary granulation)
<p>Cell description: </p> <p>Size: 15-25 µm </p> <p>Nucleus: oval with identifiable nucleoli and diffuse chromatin structure Cytoplasm: basophilic with visible golgi-zone and eye-catching azurophil granula (primary granulation)</p>
Pseudo-fragmentocytes: artefacts due to mechanical abrasion close to a scratch.
<p>Pseudo-fragmentocytes: artefacts due to mechanical abrasion close to a scratch.</p>
These so-called 'pseudo-Pelger's nuclear anomalies' with abnormal chromatin condensation and/or deficient nuclear segmentation are often found with viral infections, after chemotherapy, or with a myelodysplastic syndrome (MDS). Conversely, the true Pelger's nuclear anomaly is hereditary and without pathological significance.
<p>These so-called 'pseudo-Pelger's nuclear anomalies' with abnormal chromatin condensation and/or deficient nuclear segmentation are often found with viral infections, after chemotherapy, or with a myelodysplastic syndrome (MDS). Conversely, the true Pelger's nuclear anomaly is hereditary and without pathological significance.</p>
Bone marrow smear of a rabbit showing a megakaryocyte. The nucleus is lobulated and many azurophilic granules are found in the cytoplasm, suggesting maturity of the cell.
<p>Bone marrow smear of a rabbit showing a megakaryocyte. The nucleus is lobulated and many azurophilic granules are found in the cytoplasm, suggesting maturity of the cell. </p>
Eosinophil with large (approx. 1,5 µm) round and orange-reddish staining granules that are sharply defined and markedly larger than eosinophil granules in mice and rats.
<p>Eosinophil with large (approx. 1,5 µm) round and orange-reddish staining granules that are sharply defined and markedly larger than eosinophil granules in mice and rats.</p>