Scientific Image Gallery
Welcome to our Scientific Image Gallery. Here you can find real-life examples of cell images, mostly (but not only) from peripheral blood films, that illustrate typical morphologic characteristics pointing to specific conditions or disorders. This constitutes their diagnostic value.
Click on an image to enlarge it and display a short description.
Bone marrow histology (Giemsa stain) showing two Hodgkin cells (H). These giant cells have an oval, non-lobulated nucleus and at least one nucleolus. Reed-Sternberg cells (RS) have a lobulated nucleus with several nucleoli. Both cell types are characteristic of Hodgkin's disease and express the same surface marker CD30, which is otherwise found on activated lymphocytes.
<p>Bone marrow histology (Giemsa stain) showing two Hodgkin cells (H). These giant cells have an oval, non-lobulated nucleus and at least one nucleolus. Reed-Sternberg cells (RS) have a lobulated nucleus with several nucleoli. Both cell types are characteristic of Hodgkin's disease and express the same surface marker CD30, which is otherwise found on activated lymphocytes. </p>
Bone marrow histology (Giemsa stain) of a patient showing an infiltrating Hodgkin's lymphoma on the left side. On the right side normal haematopoietic tissue can be seen.
<p>Bone marrow histology (Giemsa stain) of a patient showing an infiltrating Hodgkin's lymphoma on the left side. On the right side normal haematopoietic tissue can be seen.</p>
Howell-Jolly bodies in the cell adjacent to the granulocyte, spherocytes, polychromasia, and a single erythroblast in a case of auto-immune haemolytic anaemia (AIHA). (Howell-Jolly bodies are DNA remnants. Polychromatic cells still contain RNA.)
<p>Howell-Jolly bodies in the cell adjacent to the granulocyte, spherocytes, polychromasia, and a single erythroblast in a case of auto-immune haemolytic anaemia (AIHA). (Howell-Jolly bodies are DNA remnants. Polychromatic cells still contain RNA.)</p>
An apparent Howell-Jolly body, caused by contaminated microscope oil, can be identified as an artefact by the fact that it moves independently over time.
<p>An apparent Howell-Jolly body, caused by contaminated microscope oil, can be identified as an artefact by the fact that it moves independently over time.</p>
An apparent Howell-Jolly body, caused by contaminated microscope oil, can be identified as an artefact by the fact that it moves independently over time.
<p>An apparent Howell-Jolly body, caused by contaminated microscope oil, can be identified as an artefact by the fact that it moves independently over time.</p>
Round residual nucleus of purple-brown colour, circular, not refactive, eccentrically placed, frequently associated with acanthocytes, target cells or Pappenheimer bodies. Incidence: post splenectomy, severe anaemia with intact spleen function, e.g. pernicious anaemia, MDS
<p>Round residual nucleus of purple-brown colour, circular, not refactive, eccentrically placed, frequently associated with acanthocytes, target cells or Pappenheimer bodies. Incidence: post splenectomy, severe anaemia with intact spleen function, e.g. pernicious anaemia, MDS</p>
Incidental detection of Borrelia recurrentis (->) in a patient initially suspected to suffer from malaria. Borrelia recurrentis is transmitted by lice and ticks and is the causative agent of relapsing fever. Like malaria, relapsing fever often is a travel-related disease that, after an incubation time of up to 2 weeks, leads to fever attacks.
<p>Incidental detection of Borrelia recurrentis (->) in a patient initially suspected to suffer from malaria. Borrelia recurrentis is transmitted by lice and ticks and is the causative agent of relapsing fever. Like malaria, relapsing fever often is a travel-related disease that, after an incubation time of up to 2 weeks, leads to fever attacks.</p>
In the peripheral blood (May-Grünwald-Giemsa stain) of this 75-year old woman with PV all three cell lineages are increased: haemoglobin concentration 16 g/dL, white blood cell count 15,000/µL, platelet count 980,000/µL. In functional iron deficiency red blood cells often are microcytic. The MCV is only 75 fL. The haematopoietic cells of the patient show a JAK2 mutation.
<p>In the peripheral blood (May-Grünwald-Giemsa stain) of this 75-year old woman with PV all three cell lineages are increased: haemoglobin concentration 16 g/dL, white blood cell count 15,000/µL, platelet count 980,000/µL. In functional iron deficiency red blood cells often are microcytic. The MCV is only 75 fL. The haematopoietic cells of the patient show a JAK2 mutation.</p>
Infectious mononucleosis is an acute condition caused by the Epstein-Barr virus (EBV). The disease is highly contagious and spreads via body secretions, especially saliva. The infection frequently goes unnoticed in children; however, mainly adolescents and young adults exhibit symptoms. Infected B lymphocytes induce a humoral (B cell) as well as a cellular (T cell) immune response which can be seen in an increased concentration of atypical lymphocytes in the blood film.
<p>Infectious mononucleosis is an acute condition caused by the Epstein-Barr virus (EBV). The disease is highly contagious and spreads via body secretions, especially saliva. The infection frequently goes unnoticed in children; however, mainly adolescents and young adults exhibit symptoms. Infected B lymphocytes induce a humoral (B cell) as well as a cellular (T cell) immune response which can be seen in an increased concentration of atypical lymphocytes in the blood film. </p>