Scientific Image Gallery
Welcome to our Scientific Image Gallery. Here you can find real-life examples of cell images, mostly (but not only) from peripheral blood films, that illustrate typical morphologic characteristics pointing to specific conditions or disorders. This constitutes their diagnostic value.
Click on an image to enlarge it and display a short description.
Monocyte with a U-shaped nucleus and grey-blue cytoplasm.
<p>Monocyte with a U-shaped nucleus and grey-blue cytoplasm.</p>
Cell description:
Size: larger than normal lymphocytes
Nucleus: round, oval, dumbbell-shaped or bilobed with little chromatin condensation and sometimes indistinct nucleolus
Cytoplasm: abundant weakly basophilic with irregular “hairy” margins
<p>Cell description: </p> <p>Size: larger than normal lymphocytes </p> <p>Nucleus: round, oval, dumbbell-shaped or bilobed with little chromatin condensation and sometimes indistinct nucleolus </p> <p>Cytoplasm: abundant weakly basophilic with irregular “hairy” margins</p>
Peripheral blood (May-Grünwald-Giemsa stain) of a patient with hairy cell leukaemia. A typical hairy cell (->) can easily be distinguished from a normal lymphocyte (lower right).
<p>Peripheral blood (May-Grünwald-Giemsa stain) of a patient with hairy cell leukaemia. A typical hairy cell (->) can easily be distinguished from a normal lymphocyte (lower right).</p>
Hairy cell from a hairy cell leukaemia. Typical are the monocytic type nuclei with loose chromatin, and the grey-blue, heterogeneous cytoplasm. The hairy protrusions may be missing in some cases.
<p>Hairy cell from a hairy cell leukaemia. Typical are the monocytic type nuclei with loose chromatin, and the grey-blue, heterogeneous cytoplasm. The hairy protrusions may be missing in some cases.</p>
Hairy cell leukaemia-variant (HCL-V).
<p>Hairy cell leukaemia-variant (HCL-V).</p>
Cell description:
Size: larger than normal lymphocytes
Nucleus: round, oval, dumbbell-shaped or bilobed with little chromatin condensation and sometimes indistinct nucleolus
Cytoplasm: abundant weakly basophilic with irregular “hairy” margins
<p>Cell description: </p> <p>Size: larger than normal lymphocytes </p> <p>Nucleus: round, oval, dumbbell-shaped or bilobed with little chromatin condensation and sometimes indistinct nucleolus </p> <p>Cytoplasm: abundant weakly basophilic with irregular “hairy” margins</p>
This 'hairy' lymphocyte comes from a person suffering from an active infection (without any malignant disease). The granula identify it as a T or an NK cell.
<p>This 'hairy' lymphocyte comes from a person suffering from an active infection (without any malignant disease). The granula identify it as a T or an NK cell.</p>
Reticulocyte staining. Characteristic HbH cell in a case of α-thalassaemia. Today, blood films are no longer investigated for HbH cells. Instead,
α-thalassaemias are diagnosed by molecular genetic tests.
<p>Reticulocyte staining. Characteristic HbH cell in a case of α-thalassaemia. Today, blood films are no longer investigated for HbH cells. Instead, </p> <p>α-thalassaemias are diagnosed by molecular genetic tests.</p>
A remarkably high and conspicuous number of megakaryocytes (->) is visible in the bone marrow histology (Giemsa stain) of a patient with CML.
<p>A remarkably high and conspicuous number of megakaryocytes (->) is visible in the bone marrow histology (Giemsa stain) of a patient with CML. </p>